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PROSTATE CANCER SCIENTIFIC RESEARCHES ABOUT HEALTH PROSTATE CARE DIETARY SUPPLEMENT There are many worldwide researches defining the high power of the organic components for human health care supplements manufacturing industry. Scientific pubblications from University in Japan, USA, Italy, Australia,... confirms the quality and efficience of the Organic Lycopene to avoid main human diseases as prostate cancer, Parkinson, Alzheimer disease and other type of cancer. The scientific staff of Pierre Italy has used all of them as scientific reference to improve, to define our organic dietary supplements... APPLY FOR DISTRIBUTION

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SCIENTIFIC RESEARCH ABOUT PROSTATE CANCER AND OTHER TYPES OF CANCER PREVENTION SYSTEMS

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THE US FOOD AND DRUG ADMINISTRATION'S EVIDENCE-BASED REVIEW FOR QUALIFIED HEALTH CLAIMS: TOMATOES LYCOPENE AND CANCER

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US FDA TOMATOES LYCOPENE AND CANCER Several studies have reported an inverse association between tomato and/or lycopene intake and the risk of some types of cancer. In 2004, the U.S. Food and Drug Administration (FDA) received two petitions for qualified health claims regarding tomatoes, lycopene, and the risk reduction for some forms of cancer. Health claims that characterize the relationship between a food or food component and a disease or health-related condition require premarket approval by FDA to be included on the labels of conventional foods and dietary supplements. Here we describe FDA’s review of the scientific data for tomato and/or lycopene intake with respect to risk reduction for certain forms of cancer. The FDA found no credible evidence to support an association between lycopene intake and a reduced risk of prostate, lung, colorectal, gastric, breast, ovarian, endometrial, or pancreatic cancer. The FDA also found no credible evidence for an assocaition between tomato consumption and a reduced risk of lung, colorectal, breast, cervical, or endometrial cancer. The FDA found very limited evidence to support an association between tomato consumption and reduced risks of prostate, ovarian, gastric, and pancreatic cancers. J Natl Cancer Inst 2007;99: 1074 – 85 / by Claudine J . Kavanaugh , Paula R . Trumbo , Kathleen C . Ellwood

Italian dietary and health food supplements businessProduzione Italiana di integratori alimentari biologici

SCIENTIFIC RESEARCHES - PROSTATE CANCER AND THE ORGANIC LYCOPENE DEVELOPMENT

Fabrica de integrador o suplemento alimenticio

1

Ansari M, Ansari S. Sanjay Gandhi Postgraduate Institute of Medical Sciences, Department of Urology and Renal transplantation, Rae Breli Road, Lucknow-UP (226014), India. ansarimsa@hotmail.com , Sanjay Gandhi Postgraduate Institute of Medical Sciences, Department of Urology and Renal transplantation, Rae Breli Road, Lucknow-UP (226014), India. Lycopene and prostate cancer. Future Oncol. 2005 Jun;1(3):425-430

 

2

Stacewicz-Sapuntzakis M, Bowen PE. Department of Human Nutrition, University of Illinois at Chicago, 1919 West Taylor St. Chicago, IL 60612, USA. Role of lycopene and tomato products in prostate health. Biochim Biophys Acta. 2005 May 30;1740(2):202-5. Epub 2005 Mar 13

 

3

Siler U, Herzog A, Spitzer V, Seifert N, Denelavas A, Hunziker PB, Barella L, Hunziker W, Lein M, Goralczyk R, Wertz K. - DSM Nutritional Products Ltd., Human Nutrition and Health, Basel, Switzerlandand. Lycopene effects on rat normal prostate and prostate tumor tissue. J Nutr. 2005 Aug;135(8):2050S-2S

 

4

Kaplan SA - Lycopene: modes of action to promote prostate health. J Urol. 2005 Aug;174(2):679; discussion 679.

 

5

Mohanty NK, Saxena S, Singh UP, Goyal NK, Arora RP. Department of Urology, V.M. Medical College & Safdarjang Hospital, New Delhi, India. Lycopene as a chemopreventive agent in the treatment of high-grade prostate intraepithelial neoplasia. Urol Oncol. 2005 Nov-Dec;23(6):383-5

 

6

Guns ES, Cowell SP. - Department of Surgery, University of British Columbia, Canada. eguns@vanhosp.bc.ca Drug Insight: lycopene in the prevention and treatment of prostate cancer. Nat Clin Pract Urol. 2005 Jan;2(1):38-43.

 

7

Fraser ML, Lee AH, Binns CW. Curtin University of Technology, School of Public Health, GPO Box U 1987, Perth WA 6845, Australia. nugget008@hotmail.com Lycopene and prostate cancer: emerging evidence Expert Rev Anticancer Ther. 2005 Oct;5(5):847-54

8

Kirsh VA, Mayne ST, Peters U, Chatterjee N, Leitzmann MF, Dixon LB, Urban DA, Crawford ED, Hayes RB. Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA. A prospective study of lycopene and tomato product intake and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev. 2006 Jan;15(1):92-8

 

9

Everson KM, McQueen CE. Drug Information Center, University of Missouri-Kansas City, 64108, USA. Lycopene for prevention and treatment of prostate cancer. Am J Health Syst Pharm. 2004 Aug 1;61(15):1562-6

 

10

Barber NJ, Barber J. Department of Urology, St George's Hospital, London, UK.Lycopene and prostate cancer. Prostate Cancer Prostatic Dis. 2002 Mar;5(1):6-12. PROSTATE CANCER AND PROSTATIC DISEASES: (2002) 5, 6-12. DOI: 10.1038/sj/pcan/4500560

 

11

Barber NJ, Barber J. Department of Urology, St George's Hospital, London, UK.Lycopene and prostate cancer. Prostate Cancer Prostatic Dis. 2002 Mar;5(1):6-12. PROSTATE CANCER AND PROSTATIC DISEASES: (2002) 5, 6-12. DOI: 10.1038/sj/pcan/4500560

 

12

Bowen PE - Department of Human Nutrition, University of Illinois at Chicago, Chicago, IL 60612. Selection of surrogate endpoint biomarkers to evaluate the efficacy of lycopene/tomatoes for the prevention/progression of prostate cancer. J Nutr. 2005 Aug;135(8):2068S-70S

 

13

Gann PH - Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.Intermediate biomarkers of lycopene/tomato effects in high-risk prostatic tissue. J Nutr. 2005 Aug;135(8):2065S-7S

 

14

Tang L, Jin T, Zeng X, Wang JS. - Department of Environmental Toxicology and The Institute of Environmental and Human Health, Texas Tech University System, Lubbock, TX; Lycopene inhibits the growth of human androgen-independent prostate cancer cells in vitro and in BALB/c nude mice. J Nutr. 2005 Feb;135(2):287-90.

 

15

Chan JM, Gann PH, Giovannucci EL. Department of Epidemiology and Biostatistics, 1600 Divisadero St, Box 1695, San - Francisco, CA 94143-1695, USA. june@uorg.ucsf.edu Role of diet in prostate cancer development and progression. J Clin Oncol. 2005 Nov 10;23(32):8152-60

 

16

Ansari MS, Gupta NP - Department of Urology, All India Institute of Medical Sciences, New Delhi 110029, India. ansarimsa@hotmail.com Lycopene: a novel drug therapy in hormone refractory metastatic prostate cancer. Urol Oncol. 2004 Sep-Oct;22(5):415-20

 

17

Obermuller-Jevic UC,Olano-Martin E, Corbacho AM, Eiserich JP,van der Vliet A, Valacchi G, Cross CE, Packer L Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of California, Davis, CA 95616, USA. Lycopene inhibits the growth of normal human prostate epithelial cells in vitro. J Nutr. 2003 Nov;133(11):3356-60.

 

18

Hwang ES, Bowen PE. - Department of Human Nutrition, University of Illinois, Chicago, IL 61801, USA. Effects of tomato paste extracts on cell proliferation, cell-cycle arrest and apoptosis in LNCaP human prostate cancer cells. Biofactors. 2005;23(2):75-84.

 

19

Chang S, Erdman JW Jr, Clinton SK, Vadiveloo M, Strom SS, Yamamura Y, Duphorne CM, Spitz MR, Amos CI, Contois JH, Gu X, Babaian RJ, Scardino PT, Hursting SD. Relationship between plasma carotenoids and prostate cancer. Nutr Cancer. 2005;53(2):127-34

 

20

Kristal AR, Schenk JM. - Fred Hutchinson Cancer Research Center, Seattle, WA 98109-4686. Directions for future epidemiological research in lycopene and prostate cancer risk. J Nutr. 2005 Aug;135(8):2037S-9S

 

21

Giovannucci E. - Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115 and Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115. Tomato Products, Lycopene, and Prostate Cancer: A Review of the Epidemiological Literature. J Nutr. 2005 Aug;135(8):2030S-2031S

 

22

Giovannucci E, Clinton SK - Harvard Medical School, Channing Laboratory, Boston, Massachusetts 02115, USA. Tomatoes, lycopene, and prostate cancer. Proc Soc Exp Biol Med 1998 Jun;218(2):129-139

 

23

Giovannucci E, Ascherio A, Rimm EB, Stampfer MJ, Colditz GA, Willett WC Channing Laboratory, Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.Intake of carotenoids and retinol in relation to risk of prostate cancer. J Natl Cancer Inst 1995 Dec 6;87(23):1767-1776

 

24

Pastori M, Pfander H, Boscoboinik D, Azzi A Institute for Biochemistry and Molecular Biology, University of Bern, Bern, CH-3012, Switzerland. Lycopene in association with alpha-tocopherol inhibits at physiological concentrations proliferation of prostate carcinoma cells. Biochem Biophys Res Commun 1998 Sep 29;250(3):582-5

 

25

Gann PH, Ma J, Giovannucci E, Willett W, Sacks FM, Hennekens CH, Stampfer MJ Department of Preventive Medicine, Northwestern University Medical School, Chicago, Illinois 60611, USA. pgann@nwu.edu Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. Cancer Res 1999 Mar 15;59(6):1225-30

 

26

Rao AV, Fleshner N, Agarwal S - Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, ON, Canada. v.rao@utoronto.ca “Serum and tissue lycopene and biomarkers of oxidation in prostate cancer patients: a case-control study”. Nutr Cancer 1999;33(2):159-64

 

27

Norrish AE, Jackson RT, Sharpe SJ, Skeaff CM - Department of Community Health, University of Auckland, New Zealand. Prostate cancer and dietary carotenoids. Am J Epidemiol 2000 Jan 15;151(2):119-23

 

28

Lu QY, Hung JC, Heber D, Go VL, Reuter VE, Cordon-Cardo C, Scher HI, Marshall JR, Zhang ZF. Center for Human Nutrition, University of California at Los Angeles School of Medicine, Los Angeles, CA 90095, USA. qlu@mednet.ucla.edu Inverse associations between plasma lycopene and other carotenoids and prostate cancer. Cancer Epidemiol Biomarkers Prev 2001 Jul;10(7):749-56

 

29

Matlaga BR, Hall MC, Stindt D, Torti FM. Department of Urology and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina.Response of hormone refractory prostate cancer to lycopene. J Urol 2001 Aug;166(2):613

 

30

Bowen, P. E. University of Illinois, Chicago, IL, 60612: pbowen@uic.edu, USA Tomato sauce supplementation reduces DNA damage in men with prostate cancer. Abstracts of Papers American Chemical Society VOL. 222 NO. 1-2,2001 PP. AGFD129. American Chemical Society CONFERENCE DATE August 26-30, 2001 CONFERENCE TITLE: 222nd National Meeting of the American Chemical Society

 

31

Van Breemen RB. Department of Medicinal Chemistry and Pharmacognosy, University of Illinois College of Pharmacy, Chicago, IL 60612. How do intermediate endpoint markers respond to lycopene in men with prostate cancer or benign prostate hyperplasia? J Nutr. 2005 Aug;135(8):2062S-4S

 

32

Matos HR, Marques SA, Gomes OF, Silva AA, Heimann JC, Di Mascio P, Medeiros MH. Departamento de Fisiologia, Universidade Federal de Sergipe, Sao Cristovao, SE, Brasil.Lycopene and ss-carotene protect in vivo iron-induced oxidative stress damage in rat prostate. Braz J Med Biol Res. 2006 Feb;39(2):203-10. Epub 2006 Feb 2

 

33

Lowe JF, Frazee LA. - Department of Pharmacy, Akron General Medical Center, Akron, Ohio. Update on prostate cancer chemoprevention. Pharmacotherapy. 2006 Mar;26(3):353-9

 

34

Wisard M, Leisinger HJ. Service d'urologie CHUV, Lausanne. [Prostate cancer prevention] - Rev Med Suisse. 2006 Jan 11;2(48):163-5

 

35

Limpens J, Schroder FH, de Ridder CM, Bolder CA, Wildhagen MF, Obermuller-Jevic UC, Kramer K, van Weerden WM. Department of Urology, Erasmus MC, Rotterdam, The Netherlands. Combined lycopene and vitamin E treatment suppresses the growth of PC-346C human prostate cancer cells in nude mice. J Nutr. 2006 May;136(5):1287-93.

 

36

Neill MG, Fleshner NE. Division of UroOncology, University Health Network, Toronto, Ontario, Canada. An update on chemoprevention strategies in prostate cancer for 2006. Curr Opin Urol. 2006 May;16(3):132-7

 

37

Clark PE, Hall MC, Borden LS Jr, Miller AA, Hu JJ, Lee WR, Stindt D, D'Agostino R Jr, Lovato J, Harmon M, Torti FM. Department of Urology and Comprehensive Cancer Center, Wake Forest University Health Sciences, Winston-Salem, North Carolina 27157, USA. peclark@wfubmc.edu Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse of prostate cancer after definitive local therapy.Urology. 2006 Jun;67(6):1257-61

 

38

Rossinow JK, Balajee AS, Gewanter RM, Ennis RD, Schiff PB, Katz AE, Geard CR. Albert Einstein College of Medicine, Bronx, NY, USA - Effects of lycopene and vitamin E on gamma-irradiated prostate cancer cells. Int J Radiat Oncol Biol Phys. 2003 Oct 1;57(2 Suppl):S348-9

 

39

Segev Y, Nativ O-Urology Department, The Bnei Zion Medical Center, Haifa. segevyakir@yahoo.com Nutrition and pharmacological treatment for prevention of prostate cancer. Harefuah. 2006 Jan;145(1):47-51, 76-7

 

40

Campbell JK, Rogers RB, Lila MA, Erdman JW Jr. Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, 905 South Goodwin Avenue, and Department of Natural Resources and Environmental Sciences, University of Illinois at Urbana-Champaign, 1201 South Dorner Drive, Urbana, Illinois 61801. Biosynthesis of (14)C-Phytoene fromTomato Cell Suspension Cultures (Lycopersicon esculentum) for Utilization in Prostate Cancer Cell Culture Studies. J Agric Food Chem. 2006 Feb 8;54(3):747-755

 

41

Tavani A, Longoni E, Bosetti C, Maso LD, Polesel J, Montella M, Ramazzotti V, Negri E, Franceschi S, Vecchia CL. - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.Intake of Selected Micronutrients and the Risk of Surgically Treated Benign Prostatic Hyperplasia: A Case-Control Study from Italy. Eur Urol. 2005 Dec 28

 

42

Chan JM, Elkin EP, Silva SJ, Broering JM, Latini DM, Carroll PR. Department of Urology, University of California-San Francisco, California 94143-1695, USA. june@uorg.ucsf.eduTotal and specific complementary and alternative medicine use in a large cohort of men with prostate cancer. Urology. 2005 Dec;66(6):1223-8

 

43

McCann SE, Ambrosone CB, Moysich KB, Brasure J, Marshall JR, Freudenheim JL, Wilkinson GS, Graham S. Intakes of selected nutrients, foods, and phytochemicals and prostate cancer risk in Western new york. Nutr Cancer. 2005;53(1):33-41.

 

44

Schroder FH, Roobol MJ, Boeve ER, de Mutsert R, Zuijdgeest-van Leeuwen SD, Kersten I, Wildhagen MF, van Helvoort A. Department of Urology, Erasmus MC Rotterdam, The Netherlands. Randomized, Double-Blind, Placebo-Controlled Crossover Study in Men with Prostate Cancer and Rising PSA: Effectiveness of a Dietary Supplement.Eur Urol. 2005 Dec;48(6):922-31. Epub 2005 Oct 17

 

45

Wirth MP, Hakenberg OW. Klinik und Poliklinik fur Urologie, Technische Universitat Dresden, Dresden. Prevention of prostate cancer - Dtsch Med Wochenschr. 2005 Sep 9;130(36):2002-4.

 

46

Sonn GA, Aronson W, Litwin MS. Department of Urology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA [2] 2Department of Health Services, UCLA School of Public Health, Los Angeles, California, USA [3] 3UCLA Jonsson Comprehensive Cancer Center, Los Angeles, California, USA. Impact of diet on prostate cancer: a review. Prostate Cancer Prostatic Dis. 2005 Aug 30; Prostate Cancer and Prostatic Diseases advance online publication, 30 August 2005; doi:10.1038/sj.pcan.4500825

 

47

Almushatat AS, Talwar D, McArdle PA, Williamson C, Sattar N, O'reilly DS, Underwood MA, McMillan DC. University Department of Surgery, Royal Infirmary, Glasgow, UK. Vitamin antioxidants, lipid peroxidation and the systemic inflammatory response in patients with prostate cancer. Int J Cancer. 2005 Aug 16; 2005 Wiley-Liss, Inc

 

48

Clinton SK. Molecular Carcinogenesis and Chemoprevention Program, The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210. Tomatoes or lycopene: a role in prostate carcinogenesis? J Nutr. 2005 Aug;135(8):2057S-9S

 

49

Tappel A. Department of Food Science and Technology, University of California, Davis, CA 95616, USA. Lysosomal and prostasomal hydrolytic enzymes and redox processes and initiation of prostate cancer. Med Hypotheses. 2005;64(6):1170-2.

 

50

Iwasaki M, Tsugane S. - Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center. Risk factors and current chemoprevention studies for prostate cancer - Nippon Rinsho. 2005 Feb;63(2):321-6

 

51

Ansari MS, Sgupta NP. Bratt O. A comparison of lycopene and orchidectomy vs orchidectomy alone in the management of advanced prostate cancer. BJU Int. 2005 Feb; 95(3):453 . BJU Int. 2005 Jan; 95(1):192. Comment on: BJU Int. 2003 Sep;92(4):375-8; discussion 378

 

52

Comhaire F, Mahmoud A. Ghent University Hospital, Gent, Belgium. Preventing diseases of the prostate in the elderly using hormones and nutriceuticals. Aging Male. 2004 Jun;7(2):155-69

 

53

Srivastava AR, Dalela D. - King George's Medical University, Lucknow, Uttar Pradesh, India. Prostate cancer: altering the natural history by dietary changes.
Natl Med J India. 2004 Sep-Oct;17(5):248-53

 

54

Jian L, Du CJ, Lee AH, Binns CW. - School of Public Health, Curtin University of Technology, Perth, Australia. Do dietary lycopene and other carotenoids protect against prostate cancer? Int J Cancer. 2004 Oct 28. (c) 2004 Wiley-Liss, Inc.

 

55

Hwang ES, Bowen PE. - Department of Human Nutrition, University of Illinois, Chicago, Illinois, U.S.A. Cell Cycle Arrest and Induction of Apoptosis by Lycopene in LNCaP Human Prostate Cancer Cells. J Med Food. 2004 Fall;7(3):284-9

 

56

Bosetti C, Talamini R, Montella M, Negri E, Conti E, Franceschi S, La Vecchia C. Istituto di Ricerche Farmacologiche "Mario Negri," Milan, Italy. Retinol, carotenoids and the risk of prostate cancer: A case-control study from Italy. Int J Cancer. 2004 Nov 20;112(4):689 - Copyright 2004 Wiley-Liss, Inc

 

57

Sanderson M, Coker AL, Logan P, Zheng W, Fadden MK. University of Texas-Houston School of Public Health at Brownsville, 80 Fort Brown, Brownsville, TX 78520; USA. Ph.: 956-554-5162 fax: 956-554-5152, e-mail: msanderson@utb.edu - Lifestyle and prostate cancer among older african-american and caucasian men in South Carolina. Cancer Causes Control. 2004 Sep;15(7):647-55

 

58

Dagnelie PC, Schuurman AG, Goldbohm RA, Van den Brandt PA. Department of Epidemiology, Maastricht University, Maastricht, The Netherlands. Dagnelie@epid.unimaas.nl Diet, anthropometric measures and prostate cancer risk: a review of prospective cohort and intervention studies. BJU Int. 2004 May;93(8):1139-50

 

59

Siler U, Barella L, Spitzer V, Schnorr J, Lein M, Goralczyk R, Wertz K. Lycopene and Vitamin E interfere with autocrine/paracrine loops in the Dunning prostate cancer model. FASEB J. 2004 Apr 14

 

60

Klein EA, Thompson IM. Section of Urologic Oncology, Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio and Department of Urology, University of Texas Health Sciences Center, San Antonio, Texas, USA. Update on chemoprevention of prostate cancer. Curr Opin Urol. 2004 May;14(3):143-149

 

61

Limpens J, van Weerden WM, Kramer K, Pallapies D, Obermuller-Jevic UC, Schroder FH.Re: Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. J Natl Cancer Inst. 2004 Apr 7;96(7):554; author reply 554-5. Comment on: J Natl Cancer Inst. 2003 Nov 5;95(21):1578-86

 

62

Kristal AR - Cancer Prevention Program, Fred Hutchinson Cancer Research Program, Seattle, Washington 98109-1024, USA. akristal@fhcrc.org Vitamin A, retinoids and carotenoids as chemopreventive agents for prostate cancer. J Urol. 2004 Feb;171(2 Pt 2):S54-8; discussion S58

 

63

Willis MS, Wians FH - Department of Pathology, The University of Texas Southwestern Medical Center, Dallas, TX, USA - The role of nutrition in preventing prostate cancer: a review of the proposed mechanism of action of various dietary substances. Clin Chim Acta 2003 Apr;330(1-2):57-83

 

64

Wu K, Erdman JW Jr, Schwartz SJ, Platz EA, Leitzmann M, Clinton SK, DeGroff V, Willett WC, Giovannucci E. Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA. kana.wu@channing.harvard.edu - Plasma and dietary carotenoids, and the risk of prostate cancer: a nested case-control study. Cancer Epidemiol Biomarkers Prev. 2004 Feb;13(2):260-9

 

65

Kim HS, Bowen P, Chen L, Duncan C, Ghosh L, Sharifi R, Christov K. Department of Human Nutrition, University of Illinois at Chicago, 1919 W. Taylor, Chicago, IL 60612, USA.Effects of tomato sauce consumption on apoptotic cell death in prostate benign hyperplasia and carcinoma. Nutr Cancer. 2003;47(1):40-7

 

66

Forbes K, Gillette K, Sehgal I. - Center for Protease Research, North Dakota State University, Fargo, North Dakota 58105, USA. Lycopene increases urokinase receptor and fails to inhibit growth or connexin expression in a metastatically passaged prostate cancer cell line: a brief communication. Exp Biol Med (Maywood). 2003 Sep;228(8):967-71

 

67

Boileau TW, Liao Z, Kim S, Lemeshow S, Erdman JW Jr, Clinton SK. Division of Nutritional Sciences, University of Illinois, Urbana-Champaign, IL (TWMB, JWE). J Natl Cancer Inst. 2003 Nov 5;95(21):1578-86. Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets

 

68

Pohar KS, Gong MC, Bahnson R, Miller EC, Clinton SK. Division of Urology, Department of Surgery, Ohio State University College of Medicine and Public Health, 4841 UHC, 456 West 10th Avenue, OH 43210, Columbus, USA, pohar-1@medctr.osu.edu Tomatoes, lycopene and prostate cancer: a clinician's guide for counseling those at risk for prostate cancer. World J Urol. 2003 May;21(1):9-14. Epub 2003 Mar 22

 

69

Pathak SK, Sharma RA, Mellon JK - Cancer Biomarkers and Prevention Group, Department of Oncology, University of Leicester, Leicester, LE2 7LX, UK.Chemoprevention of prostate cancer by diet-derived antioxidant agents and hormonal manipulation (Review). Int J Oncol 2003 Jan;22(1):5-13

 

70

Huang HY, Alberg AJ, Norkus EP, Hoffman SC, Comstock GW, Helzlsouer KJ. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. Prospective study of antioxidant micronutrients in the blood and the risk of developing prostate cancer. Am J Epidemiol 2003 Feb 15;157(4):335-44

 

71

Boyle P, Severi G, Giles GG. Division of Epidemiology and Biostatistics, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy. director.epi@ieo.it The epidemiology of prostate cancer. Urol Clin North Am. 2003 May;30(2):209-17

 

72

Richards LR, Benghuzzi H, Tucci M, Hughes J. Clinical Health Sciences Graduate Program, School of Health Related Professions, Department of Pathology and Orthopedic Surgery and Rehab University of Mississippi Medical Center, Jackson, Mississippi, USA. The synergistic effect of conventional and sustained delivery of antioxidants on LNCaP prostate cancer cell line. Biomed Sci Instrum. 2003;39:402-7

 

73

Ansari MS, Gupta NP. Department of Urology, All India Institute of Medical Science, New Delhi, India. A comparison of lycopene and orchidectomy vs orchidectomy alone in the management of advanced prostate cancer. BJU Int. 2003 Sep;92(4):375-8

 

74

Gann PH, Khachik F - Tomatoes or lycopene versus prostate cancer: is evolution anti-reductionist? J Natl Cancer Inst. 2003 Nov 5;95(21):1563-5

 

75

Miano L. - Clinica Urologica, II Facolta di Medicina e Chirurgia, Universita di Roma La Sapienza, Rome, Italy. Mediterranean diet, micronutrients and prostate carcinoma: a rationale approach to primary prevention of prostate cancer. Arch Ital Urol Androl. 2003 Sep; 75(3): 166-78

 

76

Crawford ED. Section of Urologic Oncology, Division of Urology, University of Colorado Health Science Center and the University of Colorado Cancer Center, Denver, Colorado 80262, USA. david.crawford@uchsc.edu Epidemiology of prostate cancer. Urology. 2003 Dec 22;62(6 Suppl 1):3-12

 

77

Kotake-Nara E, Kushiro M, Zhang H, Sugawara T, Miyashita K, Nagao A. Department of Bioresources Chemistry, Graduate School of Fisheries Science, Hokkaido University, 3-1-1 Hakodate 041-8611, Japan and. National Food Research Institute, 2-1-12 Kannondai, Tsukuba, Ibaraki 305-8642, Japan. Carotenoids Affect Proliferation of Human Prostate Cancer Cells. J Nutr 2001 Dec;131(12):3303-3306

 

78

Giovannucci E, Rimm EB, Liu Y, Stampfer MJ, Willett WC. Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. edward.giovannucci@channing.harvard.edu A prospective study of tomato products, lycopene, and prostate cancer risk. J Natl Cancer Inst 2002 Mar 6;94(5):391-8

 

79

Grant WB - Calcium, lycopene, vitamin D and prostate cancer. Prostate 2000 Feb 15;42(3):243

 

80

Vogt TM, Mayne ST, Graubard BI, Swanson CA, Sowell AL, Schoenberg JB, Swanson GM, Greenberg RS, Hoover RN, Hayes RB, Ziegler RG. Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA. vogtt@exchange.nih.gov Serum lycopene, other serum carotenoids, and risk of prostate cancer in US Blacks and Whites. Am J Epidemiol 2002 Jun 1;155(11):1023-32

 

81

Giovannucci E - Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1812 Longwood Avenue, Boston, MA 02115, USA. Edward.giovannucci@channing.harvard.edu A review of epidemiologic studies of tomatoes, lycopene, and prostate cancer. Exp Biol Med (Maywood) 2002 Nov;227(10):852-9

 

82

Minorsky PV- Department of Natural Sciences, Mercy College, Dobbs Ferry, NY 10522, USA. Lycopene and the prevention of prostate cancer: the love apple lives up to its name. Plant Physiol 2002 Nov;130(3):1077

 

83

Kucuk O, Sarkar FH, Djuric Z, Sakr W, Pollak MN, Khachik F, Banerjee M, Bertram JS, Wood DP Jr. Division of Hematology and Oncology, 3990 John R, Barbara Ann Karmanos Cancer Institute, Wayne State University, 5 Hudson, Detroit, MI 48201, USA. kucuko@karmanos.org Effects of lycopene supplementation in patients with localized prostate cancer. Exp Biol Med (Maywood) 2002 Nov;227(10):881-5

 

84

Hadley CW, Miller EC, Schwartz SJ, Clinton SK. - Department of Food Science and Technology, Division of Hematology and Oncology, The James Cancer Hospital and Solove Research Institute, The Ohio State University, 320 W. 10th Avenue, Columbus, OH 43210, USA. Tomatoes, lycopene, and prostate cancer: progress and promise. Exp Biol Med (Maywood) 2002 Nov;227(10):869-80

 

85

Hadley CW, Miller EC, Schwartz SJ, Clinton SK. - Department of Food Science and Technology, Division of Hematology and Oncology, The James Cancer Hospital and Solove Research Institute, The Ohio State University, 320 W. 10th Avenue, Columbus, OH 43210, USA. Tomatoes, lycopene, and prostate cancer: progress and promise. Exp Biol Med (Maywood) 2002 Nov;227(10):869-80

 

86

Fleshner N, Agarwal S, Rao V. University of Toronto, Ontario, Canada. Serum and tissue lycopene and biomarkers of oxidation in prostate cancer patients: a case control study. Prostate Cancer Prostatic Dis 2000 Dec;3(S1):S13

 

87

Clinton SK, Emenhiser C, Schwartz SJ, Bostwick DG, Williams AW, Moore BJ, Erdman JW Jr Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115-6084, USA. cis-trans lycopene isomers, carotenoids, and retinol in the human prostate. Cancer Epidemiol Biomarkers Prev 1996 Oct;5(10):823-833

 

88

Miller EC, Giovannucci E, Erdman JW Jr, Bahnson R, Schwartz SJ, Clinton SK. Division of Hematology and Oncology, James Cancer Hospital, Solove Research Institute, Ohio State University Medical Center, Columbus, OH, USA. Tomato products, lycopene, and prostate cancer risk. Urol Clin North Am 2002 Feb;29(1):83-93

 

89

Bowen P, Chen L, Stacewicz-Sapuntzakis M, Duncan C, Sharifi R, Ghosh L, Kim HS, Christov-Tzelkov K, van Breemen R - Department of Human Nutrition and Dietetics, m/c 517, University of Illinois, 1919 West Taylor Street, Chicago, IL 60612, USA. pbowen@uic.eduTomato sauce supplementation and prostate cancer: lycopene accumulation and modulation of biomarkers of carcinogenesis. Exp Biol Med (Maywood) 2002 Nov;227(10):886-93

 

90

Mills PK, Beeson WL, Phillips RL, Fraser GE - Department of Preventive Medicine, Loma Linda University School of Medicine, CA 92350. Cohort study of diet, lifestyle, and prostate cancer in Adventist men. Cancer 1989 Aug 1;64(3):598-604

 

91

World Cancer Research Fund/American Institute for Cancer Research Food Nutrition and Prevention of Cancer: a global perspective. American Institute for Cancer Research, Washington DC, 1997

 

92

Hsing AW, Comstock GW, Abbey H, Polk BF - Department of Epidemiology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD. Serologic precursors of cancer. Retinol, carotenoids, and tocopherol and risk of prostate cancer. J Natl Cancer Inst 1990 Jun 6;82(11):941-946

 

93

Olson KB, Pienta KJ - Vitamins A and E: further clues for prostate cancer prevention. J Natl Cancer Inst 1998 Mar 18;90(6):414-415 - Comment on: J Natl Cancer Inst 1998 Mar 18;90(6):440-6

 

94

Nomura AM, Stemmermann GN, Lee J, Craft NE - Japan-Hawaii Cancer Study, Kuakini Medical Center, Honolulu, Hawaii 96817, USA. Serum micronutrients and prostate cancer in Japanese Americans in Hawaii. Cancer Epidemiol Biomarkers Prev 1997 Jul;6(7):487-491

 

95

Giovannucci E, Rimm EB, Stampfer MJ, Colditz GA, Willett WC Department of Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.Diabetes mellitus and risk of prostate cancer (United States). Cancer Causes Control 1998 Jan;9(1):3-9

 

96

Rentzepis MJ; Newmark H; Lipkin M; Fair WR; Tomassi M; Huryk R; Heston WDWLycopene does not inhibit the growth of subcutaneously implanted LNCaP tumor cells in nude mice: Implications for chemoprevention. JOURNAL OF UROLOGY 1998, Vol 159, Iss 5, pp 13-13

 

97

Yoshizawa K, Willett WC, Morris SJ, Stampfer MJ, Spiegelman D, Rimm EB, Giovannucci E Department of Nutrition, Harvard School of Public Health, Boston, MA, USA. Study of prediagnostic selenium level in toenails and the risk of advanced prostate cancer. J Natl Cancer Inst 1998 Aug 19;90(16):1219-1224 / Comment in: J Natl Cancer Inst 1998 Aug 19;90(16):1184-5

 

98

Hayes RB, Ziegler RG, Gridley G, Swanson C, Greenberg RS, Swanson GM, Schoenberg JB, Silverman DT, Brown LM, Pottern LM, Liff J, Schwartz AG, Fraumeni JF Jr, Hoover RN Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA. hayesr@epndce.nci.nih.gov Dietary factors and risks for prostate cancer among blacks and whites in the United States. Cancer Epidemiol Biomarkers Prev 1999 Jan;8(1):25-34

 

99

Fleshner NE, Klotz LH - Department of Surgery, Toronto Sunnybrook Regional Cancer Center, University of Toronto, Canada. neil.fleshner@utoronto.ca Diet, androgens, oxidative stress and prostate cancer susceptibility. Cancer Metastasis Rev 1998-99;17(4):325-30

 

100

Grant WB - NASA Langley Research Center, Hampton, VA, USA. wbgrant@norfolk.infi.net An ecologic study of dietary links to prostate cancer. Altern Med Rev 1999 Jun;4(3):162-9

 

101

Kumar NB, Besterman-Dahan K Department of Nutrition, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA. Nutrients in the Chemoprevention of Prostate Cancer: Current and Future Prospects. Cancer Control 1999 Nov;6(6):580-586

 

102

Kelloff GJ, Lieberman R, Steele VE, Boone CW, Lubet RA, Kopelovitch L, Malone WA, Crowell JA, Sigman CC National Cancer Institute, Division of Cancer Prevention, Chemoprevention Branch, Bethesda, MD 20892, USA. Chemoprevention of prostate cancer: concepts and strategies. Eur Urol 1999;35(5-6):342-50

 

103

Thomas JA - Department of Pharmacology, University of Texas Health Science Center, San Antonio, USA. Diet, micronutrients, and the prostate gland. Nutr Rev 1999 Apr;57(4):95-103

 

104

Kristal AR, Cohen JH - Cancer Prevention Research Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. Invited commentary: tomatoes, lycopene, and prostate cancer. How strong is the evidence? Am J Epidemiol 2000 Jan 15;151(2):124-7; discussion 128-30

 

105

Clinton SK - The dietary antioxidant network and prostate carcinoma. Cancer 1999 Nov 1;86(9):1629-31

 

106

Guttenplan JB, Chen M, Kosinska W, Thompson S, Zhao Z, Cohen LA Division of Basic Sciences/Biochemistry, New York University, Dental Center, 345 E. 24th St., New York, 10100, NY, USA Effects of a lycopene-rich diet on spontaneous and benzo[a]pyrene induced mutagenesis in porstate, colon, and lung of the lac Z mouse. Cancer Lett 2001 Mar 10;164(1):1-6

 

107

Cristoni A, Di Pierro F, Bombardelli E - Scientific Department, Indena S.p.A., Viale Ortles 12, 20139, Milan, Italy Botanical derivatives for the prostate. Fitoterapia 2000 Aug;71 Suppl 1:S21-S28

 

108

Imaida K, Tamano S, Kato K, Ikeda Y, Asamoto M, Takahashi S, Nir Z, Murakoshi M, Nishino H, Shirai T 1st Department of Pathology Nagoya City University Medical School, 1-Kawasumi, Mizuho-ku, Nagoya 467-8601, Japan. imaida@med.nagoya-cu.ac.jp - Lack of chemopreventive effects of lycopene and curcumin on experimental rat prostate carcinogenesis. Carcinogenesis 2001 Mar;22(3):467-72

 

109

Mucci LA, Tamimi R, Lagiou P, Trichopoulou A, Benetou V, Spanos E, Trichopoulos D. Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Department of Hygiene and Epidemiology, University of Athens Medical School, and Biomed International Diagnostic Center, Athens, Greece. Are dietary influences on the risk of prostate cancer mediated through the insulin-like growth factor system? BJU Int 2001 Jun;87(9):814-20

 

110

De la Taille, A.; Katz, A.; Vacherot, F.; Saint, F.; Salomon, L.; Cicco, A.; Abbou, C. C.; Chopin, D. K. Centre de Recherche chirurgicale, Service d'Urologie, H .pital Henri Mondor, 54, boulevard du Mar .chal de Lattre de Tassigny, F94100 Cr.teil. ad399@hotmail.com - Cancer of the prostate: influence of nutritional factors. Vitamins, antioxidants and trace elements  - Presse Med VOL. 30 NO. 11 2001 Mar 24 PP. 557-60

 

111

Schroder, Fritz H.; Kranse, Ries; Dijk, Mathilde A.; Blom, Jan H. M.; van Kemenade, Monique; Dagnelie, Pieter C.; Tijburg, Lianne M.; Weststrate, Jan A.  - Rotterdam, Netherlands Dietary intervention in prostate cancer patients. Results of a randomized, double blind placebo controlled cross-over study.   Journal of Urology    VOL. 165  NO. 5 Supplement   May, 2001   PP. 65. June 02-07, 2001  Annual Meeting of the American Urological Association, Inc

 

112

Kucuk O, Sarkar FH, Sakr W, Djuric Z, Pollak MN, Khachik F, Li YW, Banerjee M, Grignon D, Bertram JS, Crissman JD, Pontes EJ, Wood DP Jr. Division of Hematology and Oncology, Wayne State University, and Barbara Ann Karmanos Cancer Institute, Detroit, MI 48201, USA. kucuko@karmanos.org Phase II randomized clinical trial of lycopene supplementation before radical prostatectomy. Cancer Epidemiol Biomarkers Prev 2001 Aug;10(8):861-868

 

113

Kucuk O, Wood DP Jr. - Re: Response of hormone refractory prostate cancer to lycopene. J Urol 2002 Feb;167(2 Pt 1):651

 

114

van Breemen RB, Xu X, Viana MA, Chen L, Stacewicz-Sapuntzakis M, Duncan C, Bowen PE, Sharifi R. Department of Medicinal Chemistry and Pharmacognosy, General Clinical Research Center, and Department of Human Nutrition and Dietetics, University of Illinois at Chicago, Chicago, Illinois 60612, and Department of Urology, University of Illinois at Chicago and Westside Veterans Administration Hospital, Chicago, Illinois 60612. Liquid Chromatography-Mass Spectrometry of cis- and all-trans-Lycopene in Human Serum and Prostate Tissue after Dietary Supplementation with Tomato Sauce. J Agric Food Chem 2002 Apr 10;50(8):2214-2219

 

115

Kotake-Nara E, Kim SJ, Kobori M, Miyashita K, Nagao A. Department of Bioresources Chemistry, Graduate School of Fisheries Science, Hokkaido University, Japan. Acyclo-retinoic acid induces apoptosis in human prostate cancer cells. Anticancer Res 2002 Mar-Apr;22(2A):689-95

 

116

McMILLAN DC, Talwar D, Sattar N, Underwood M, St J O'Reilly D, McARDLE C. University Department of Surgery, Glasgow The relationship between reduced vitamin antioxidant concentrations and the systemic inflammatory response in patients with common solid tumours. Clin Nutr 2002 Apr;21(2):161-164

 

117

Schuurman AG, Goldbohm RA, Brants HA, van den Brandt PA. Department of Epidemiology, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands. A prospective cohort study on intake of retinol, vitamins C and E, and carotenoids and prostate cancer risk (Netherlands). Cancer Causes Control 2002 Aug;13(6):573-82

 

118

Van Gils CH, Bostick RM, Stern MC, Taylor JA. Molecular and Genetic Epidemiology Section, Laboratory of Molecular Carcinogenesis. National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina 27709, USA. Differences in base excision repair capacity may modulate the effect of dietary antioxidant intake on prostate cancer risk: an example of polymorphisms in the XRCC1 gene.

 

119

Cohen LA. American Health Foundation, Valhalla, New York 10595, USA. Lcohen@AHF.org Nutrition and prostate cancer: a review. Ann N Y Acad Sci 2002 Jun;963:148-55

 

120

Kucuk O. Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, Michigan 48201, USA. kucuko@karmanos.org Chemoprevention of prostate cancer.Cancer Metastasis Rev 2002;21(2):111-24

 

121

Oh WK, Small EJ. Lank Center for Genitourinary Oncology, Department of Adult Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA. Complementary and alternative therapies in prostate cancer. Semin Oncol 2002 Dec;29(6):575-84

 

122

Gallagher RP, Kutynec CL. Clinical Professor, Department of Health Care and Epidemiology, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia. Diet, micronutrients and prostate cancer: a review of the evidence. Can J Urol. 1997 Jun;4(2 Supp 1):22-27

 

123

Ansari MS, Gupta NP, Hemal AK. Department of Urology, All India Institute of Medical Sciences, New Delhi-110029, India. ansarimsa@hotmail.com Chemoprevention of carcinoma prostate: a review. Int Urol Nephrol. 2002;34(2):207-14

 

124

Clinton SK, Emenhiser C, Schwartz SJ, Bostwick DG, Williams AW, Moore BJ, Erdman JW Jr Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115-6084, USA. cis-trans lycopene isomers, carotenoids, and retinol in the human prostate. Cancer Epidemiol Biomarkers Prev 1996 Oct;5(10):823-833

 

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PREVENTION OF PROSTATE INFLAMMATION - HEALTH CARE SUPPLEMENTS MANUFACTURING

 

 

 

HEALTH PROFESSIONAL RESEARCH ABOUT CANCER RISK AND LYCOPENE In 1986 a survey of food intake was sent to 47894 health care professionals; follow-up surveys were sent in 1988, 1990, and 1992. The information was analyzed for trends in eating habits and various diseases, and consumption of several carotenoids was evaluated for a possible association with reduced risk of prostate cancer. Only lycopene was associated with a risk reduction (relative risk [RR] = 0.79, 95% confidence interval [CI] = 0.64-0.99). The foods associated with significant risk reduction were tomato sauce, pizza, and strawberries; the risk reduction for uncooked tomatoes was not significant. Tomato sauce and pizza are rich sources of lycopene, whereas strawberries, although red, do not contain lycopene. Tomato juice did not show an association, perhaps, the authors hypothesized, because of its low consumption. The association with strawberries was unexplained. The authors concluded that consumption of tomato-based foods may be linked to a reduced risk of prostate cancer.

 

 

ORGANIC LYCOPENE TO THE FOOD SUPPLEMENTS INDUSTRY BY PIERRE GROUP - THE PERFECT ANTIOXIDANT MADE IN ITALY

 

The organic lycopene is an exclusive product worldwide patented by Pierre Group Italy as the perfect antioxidant extracted without solvents or any chemical process directly from ripe red tomatoes... to produce the uniques organic dietary and health supplements products of the health market

LYCOPENE SOURCES Lycopene is a carotenoid, a group of compounds present in many fresh fruits and vegetables. There are more than 750 types of carotenoids in nature; however, only 20 of these have been found in human blood and tissues. The carotenoid most often present in human blood is lycopene ,followed by b -carotene, lutein and zeaxanthin.

 

 RED RIPE TOMATOES THE MAIN SOURCE OF LYCOPENE and their derivatives are the main natural source of lycopene giving approximately 85% of all lycopene in the human body. The amount of lycopene in tomatoes depends the quality of fruit, the environment and cultivation procedures. Usually, the content of lycopene in red-ripe tomatoes is 30-80 mg/kg of fresh product, but it could be more than 150-300 mg/kg in some selected species obtained by traditional hybridization techniques.
PROPERTIES OF ORGANIC LYCOPENE the organic lycopene has a very strong antioxidant power, as antioxidant contrasts the destructive action of free radicals in the human body (which are seriously dangerous for the cells and tissues) protects and prevents against several diseases... SEE FULL INFORMATION

   
  Health prostate organic dietary supplement, after 45 yearsold, men may experience undesired growth of the prostate due to an inflammatory process that can degenerate into cancer. Prostate Health + effectiveness plus, is a special blend of antioxidants, saw palmetto, ginseng and zinc aids in the prevention and reduction of risk factors that cause inflammation of the prostate, produced by Pierre Group in Italy Lycodeep dietary supplement - Aanti aging reducing wrinkles Lycodeep effectively counteracts the aging of the skin by reducing wrinkles and improving the thickness and sagging skin. Lycodeep is the only supplement with "Organic Lycopene" specially formulated for the protection and beautification of the skin. Lycodeep is useful in cellulite treatment. Organic Lycopene coming from Italian tomatoes Lycomplete dietary supplement with organic lycopene is a nutraceutical excellence with Organic Lycopene and other natural active ingredients acting synergistically as antioxidant treatment, specific and effective against oxidative stress. Lycomplete normalizes the value of oxidative stress. Oxidative stress is evident especially in the onset of serious diseases such as cancer, cardiovascular diseases, diabetes and others Lycosport organic dietary supplement to improve performance, Lycosport with organic lycopene, produced in Italy by Pierre Group, is a nutraceutical dietary supplement for the improvement of sports performance. Lycosport is distinguished by its special formulation, consisting of a balanced mixture of natural compounds, antioxidants and amino acids that helps to improve athletic conditions
 

Health Prostate Dietary

Lycodeep skin care supplement

Lycomplete heart supplement

Lycosport athlete supplements

  Licofor is a private label dietary supplement produced to the Barcelona Spain company Bama Geve Vitilicaps nutraceutical product with organic lycopene, produced in private label for Lyconcepts Santo Domingo Naturmio dietary supplement with our organic lycopene produced for Private label to the Italian company Sirton Medicare Spa Milano Licofor dietary supplement produced with our organic lycopene, Private Label product to the company Farmigea in Pisa Italy
 

Lycocor for Italian market

Vitilicaps for Santo Domingo market

Naturmio women for Italian market

Lycofor (eyes optic) for Italian market

 

We offer our full dietary, food and health care supplements manufacturing knowledge plus our engineering capabilities to create, design, produce new supplement products, in Private label, for manufacturers and distributors.

 

Naturmio Health Prostate for Italy

Lycocor for Spain and Portugal market

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WE PRODUCE ORGANIC LYCOPENE THE MOST IMPORTANT ANTIOXIDANT EXTRACTED FROM RED-RIPE TOMATOS

Pierre Group srl is an Italian manufacturer of organic dietary supplements using made in Italy organic lycopene health care supplementsdietary care supplements manufacturer, organic healthy suppliers, organic medicine pills manufacturing, Italian pharmaceutical technology supply, anticancer medicine vendors, organic lycopene manufacturers. Our mission is to produce the best health and dietary care products for distributors in Europe, USA, Asia Middle East... including the following markets: Italy, Austria, France, USA, Netherlands, England, Scotland, Russia, Spain, Ukraine, Greece, California, Texas, New York, Florida, Illinois, Atlanta in the US, Panama, Australia, Japan, China, India, Chile, Argentina, Brazil, Uruguay, Colombia, Ecuador, Perů, Brasil, Belgium, Saudi Arabia, Oman, Dubai, China, Thailand, Taipei, Finland, Poland, Germany, Norway, England, Romania, Kuwait, Dubai, Oman, UAE, Qatar, Mexico, Uruguay, Paraguay, Costa Rica, Republica Dominicana, Ireland Great Britain, Russia, Scotland, Bolivia, England, Sweden, Canada, the United States, South Korea, Kuwait, China, Japan, Oman, Bahrain, Denmark, Holland, Spain, Colombia, Nicaragua, Puerto Rico, Czech Republic, India, Thailand... supporting the vip wholesale dietary and health supplements distributors worldwide

 

Pierre Group an Italian dietary supplement and beauty care cosmetics manufacturing industry with facilities in Galatina Salento, South of Italy, a certified industry of organic skin care products thanks to our international patent to produce organic lycopene... made in Italy

 

Made in Italy organic dietary supplement and cosmetics manufacturer suppliers, organic producer of health beauty care cosmetics for beauty salon and wholesale distributors in China, Asia, USA, Europe, Africa, Canada, South America and Middle East vendors

 

FOR INFO AND CUSTOMER SERVICES CALL OUR MANUFACTURING FACILITIES: +39.333.6371.644

 

Italian cosmetic manufacturing, industrial manufacturer of beauty care cosmetics for beauty salon and wholesale distributors in China, Asia, USA, Europe, Africa, Canada, South America and Middle East

Nickel tested, each of our dietary supplement product is nickel tested

Our full collection of products are Paraben Free

We use only organic lycopene, coming from our organic Italian tomatoes using a biological extraction co2 system

We do not use chemical solutions or agents to extract the lycopene from tomatoes, we use only the biological extraction system with critical co2 manufacturing process

Non GMO (genetically modified organism) used by Pierre Group for cosmetics and dietary supplement products

Each of our supplements and cosmetics are sodium free to guarantee best sensation and health to your skin

All products of our collection are not tested on animals

About Pierre Group Italy   Dietary supplements   Health food supplement   Made in Italy   Organic lycopene producers   Contact Us

 

 

 

Site Map - We invite you to visit our biological health and organic dietary food supplement web pages:

 

Italian organic dietary products  dietary supplements manufacturing  health food supplements manufacturer suppliers  organic supplements wholesale distributors  cardiovascular heart health care supplements  made in italy hearth supplements lycomplete pills  prostate support supplements pharmaceutical USA health care  health prostate organic food supplement  organic sports supplement manufacturing industry  athletes US health food manufacturer for distribution lycosport  skin care food dietary supplements industrial production  women beauty care dietary supplements manufacturing lycodeep  organic lycopene manufacturers vendors for distributors  antioxidants health food supplement US products supply  Italian organic lycopene for private label health supplement  Italian world patented products  Canada certified organic health food medicine technology  Italian organic lycopene properties versus synthetic lycopene market  organic lycopene versus natural lycopene technical specifications  private label production of health dietary supplements  China health food dietary supplements lycocor Spain  organic heart supplements naturmio private label Italy  health food supplement industrial production vitilicaps Santo Domingo  nutraceutical organic lycopene private label for licofor Italy  Italian organic lycopene manufacturing industry  industrial manufacturing process of organic lycopene supplements  supplement products and distributors deals  dietary online store  distribution request

 

Italian beauty skin care comsetics manufacturer and organic health care dietary supplement manufacturing industry using organic lycopene made in Italy

 

PIERRE GROUP SRL "THE ITALIAN ORGANIC DIETARY AND HEALTH LYCOPENE SUPPLEMENTS MANUFACTURING INDUSTRY"

 

Manufacturing facilities - SP 362 Km 17,650 Zona Industriale, 73013 Galatina Lecce, Salento - Italy
Export offices in Italy (English + Spanish + Italian): +39.333.6371.644
Sales offices in England UK: +44.7935.999.251

 

Web: www.supplementsmanufacturing.com                Email: info@supplementsmanufacturing.com

 

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